Synthesis intermediates
Mandelic acid is used as a defined starting material for other chemical products. [3] [4]
CHEMICAL PROFILE CAS 90-64-2
Properties, Uses, pKa, Safety,
Comparisons & Suppliers
Mandelic acid has a hydroxyl-bearing carbon between a benzene ring and a carboxyl group. That carbon is chiral, so a DL product is a different stereochemical choice from an R or S product. [1]
Identity focus: Solid · DL identity. Aqueous pKa values depend on conditions; product assay is a separate measurement.
THE ESSENTIALS
The molecule combines a ring, a separate hydroxyl, and one acidic carboxyl group. The hydroxyl-bearing carbon is the point where its three-dimensional forms differ.
Mandelic acid has a hydroxyl-bearing carbon between a benzene ring and a carboxyl group. That carbon is chiral, so a DL product is a different stereochemical choice from an R or S product. [1] [3]
Condensed connectivity schematic; see the specified stereochemical identity below. [1]
Mandelic acid is used as a defined starting material for other chemical products. [3] [4]
The linked Sigma listing cites research on DL-mandelic-acid oxidation. [3] [4]
Mandelic acid is used in cosmetic formulation contexts. [3] [4]
The supplier section separates package size, assay, grade, and market context for three named products. [4] [4]
GO A LITTLE DEEPER
The molecule combines a ring, a separate hydroxyl, and one acidic carboxyl group. The hydroxyl-bearing carbon is the point where its three-dimensional forms differ. [1]
Lactic acid has a methyl group where mandelic acid has a phenyl ring. Both have an alpha-hydroxyl, but the aromatic ring changes the structure and product identity. A high chemical assay does not establish enantiomeric purity. [1] [4] [5] [6]
The selected products are DL-mandelic acid, CAS 90-64-2. R- and S-mandelic acid are separate stereochemical products. The connectivity drawing is not an enantiomer assignment. Numeric pKa is omitted because the reviewed record did not provide a verified value. [1] [2] [4] [5] [6]
Acid–base reference values describe equilibria under specified conditions. They are not a substitute for a validated formulation or an assay on the purchased lot.
MAKE THE CONNECTION
Similar names and functional groups do not mean interchangeable chemicals.
SIDE-BY-SIDE COMPARISON
Fixed comparison for this prototype. Acid selectors are disabled; additional comparisons are coming later.
| Property | Mandelic Acid | Lactic Acid |
|---|---|---|
| Molecular formula | C₈H₈O₃ [1] | C₃H₆O₃ [7] |
| Molecular weight | 152.15 g/mol [1] | 90.08 g/mol [7] |
| Carbon atoms | 8 [1] | 3 [7] |
| Carboxyl groups | 1 [1] | 1 [7] |
| Structure | C₆H₅–CH(OH)–COOH [1] | CH₃–CH(OH)–COOH [7] |
| Chemical family | Aromatic hydroxycarboxylic acid [1] | Hydroxymonocarboxylic acid [7] |
| Identity focus | Solid · DL identity [1] | Commercial liquids / aqueous solutions [7] |
Use mandelic acid when the procedure needs its aromatic alpha-hydroxy framework and specified stereochemistry. Use lactic acid for the methyl-bearing framework. In chiral work, a DL supply is insufficient when the method requires a single enantiomer. [1] [3] [7]
Match C₆H₅–CH(OH)–COOH and the method’s required chemical form.
Match CH₃–CH(OH)–COOH; verify the identity before substituting a related acid.
Before choosing: match the reaction or formulation, then verify the exact form, grade, assay basis, and impurities. These contexts do not establish suitability for an industrial or regulated application.
FROM STRUCTURE TO APPLICATION
SOURCE WITH CONTEXT
Compare specific products and package options. Listings are not ranked recommendations.
Package sizes stay grouped under the supplier product. Assay methods, product forms, and regional markets remain visible. Specify DL, R, or S form and optical-purity requirements separately from chemical assay.
Scroll horizontally if needed. Supplier and package identity stay visible.
| Supplier | Product / Grade | Purity / Assay | Package Size | Public Price | Normalized Price | Documentation | Last Checked | Action |
|---|---|---|---|---|---|---|---|---|
| Sigma-AldrichMandelic Acid | For synthesis · DL form8069130250 | ≥99.0% (acidimetric) | 250 g | $63.60USD · US public price | Not comparedGrades, assay bases, or forms differ | Document notes: Sigma-Aldrich
| View Product: Sigma-Aldrich, 8069130250 (opens new tab) | |
| For synthesis · DL form8069131000 | ≥99.0% (acidimetric) | 1 kg | $195.00USD · US public price | Not comparedGrades, assay bases, or forms differ | View Product: Sigma-Aldrich, 8069131000 (opens new tab) | |||
| TCIMandelic Acid | Check supplierM0038DL form · CAS 90-64-2 | >99.0% (GC and titration) | 25 g | $33.00USD · US public price | Not comparedGrades, assay bases, or forms differ | Document notes: TCI
| View Product: TCI, M0038 (opens new tab) | |
| Check supplierM0038DL form · CAS 90-64-2 | >99.0% (GC and titration) | 500 g | $89.00USD · US public price | Not comparedGrades, assay bases, or forms differ | View Product: TCI, M0038 (opens new tab) | |||
| FUJIFILM WakoMandelic Acid | Wako Special Grade · DL form013-03612 | ≥99.0% (titration) | 25 g | ¥4,400JPY · Japan suggested price (tax excluded) | Not comparedDifferent currency / market | COA lookup on product page (opens new tab)SDS PDF · Japan/JIS English (opens new tab)COOCheck supplier Document notes: FUJIFILM Wako
| View Product: FUJIFILM Wako, 013-03612 (opens new tab) | |
| Wako Special Grade · DL form017-03615 | ≥99.0% (titration) | 500 g | ¥21,800JPY · Japan suggested price (tax excluded) | Not comparedDifferent currency / market | View Product: FUJIFILM Wako, 017-03615 (opens new tab) |
Mandelic Acid
For synthesis · DL form
Last checked:
Mandelic Acid
Check supplier
DL form · CAS 90-64-2
Last checked:
Mandelic Acid
Wako Special Grade · DL form
Last checked:
COA = Certificate of Analysis · SDS = Safety Data Sheet · COO = Certificate of Origin.
Lookup means a retrieval option was visible, not that a lot certificate was reviewed. Check supplier means availability or the applicable document was not verified.
Prices may vary by quantity, account, contract, geography, and availability. These products have different grades, assay bases, or forms; no normalized comparison is shown. Foreign-market prices are reference listings only. No currency conversion, mass-to-volume conversion, or ranking is applied. Confirm equivalent specifications and a current quote before comparison. [4] [5] [6]
Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices.
Only the displayed identity, specification, packages, public prices and stated documentation evidence were reviewed. Current stock, lead times, shipping eligibility, contract pricing, lot certificates, and regulatory suitability are unverified.
There are no paid placements. Future paid listings will show “Sponsored” in both views; payment will not determine chemistry interpretation or imply a ranking.
PLAN A LARGER ORDER
Turn your requirements into a clear supplier brief.
A BUYER’S CHECKLIST
Selections remain only while this page is open.
FOR YOUR REFERENCE
Identity, product reference properties, and handling context.
Connectivity SMILES describes connectivity; it is not an independent stereochemical assignment. CAS and product-form distinctions are supported by the supplier listings. [1] [4] [5] [6]
Sigma lists crystals with melting range 119–121 °C and water solubility 139 g/L without a displayed temperature. This is a product reference, not a validated formulation limit. [4] [5] [6]
Hydrate, concentration, stereoisomer, and temperature can change the relevant specification. Product reference data are not a reviewed lot certificate.
A numeric pKa was not verified for the selected identity in this review; no value is inferred. [2]
Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices.
Temperature, ionic strength, and the use of activities versus concentrations matter in quantitative work. These reference values are not buffer recipes.
Match chemical form, concentration, region, and product code. Use its handling, storage, incompatibility, first-aid and disposal guidance alongside the workplace risk assessment.
A verified Japan/JIS English SDS is linked separately under supplier documentation; confirm the applicable local version. This profile is not a substitute for that document.
Review supplier documentationCOMMON QUESTIONS
The molecule combines a ring, a separate hydroxyl, and one acidic carboxyl group. The hydroxyl-bearing carbon is the point where its three-dimensional forms differ. [1]
Mandelic acid adds an aromatic phenyl group where lactic acid has a methyl group. The shared alpha-hydroxy-acid motif does not make either a substitute reagent or establish equivalent formulation behavior. [7]
Specify DL, R, or S form and optical-purity requirements separately from chemical assay. [4]
No. The table retains differing grades, assay bases, forms, and markets. No normalized ranking or currency conversion is applied. [5]
Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices. [6]
The RFQ is a prototype that prepares an on-screen brief. Nothing is sent to suppliers. Confirm actual bulk terms directly with the supplier. [4]
TRACE THE INFORMATION
Identity and compiled reference values are separated from supplier-specific specifications. Structural comparisons and buyer guidance are editorial interpretation. Sources were checked October 3, 2026; supplier information can change.
Official PUG REST identity record: formula, molecular weight, IUPAC name, and connectivity SMILES.
No usable numeric entry was retrieved for this selected identity; numeric pKa is deliberately omitted.
Compiled application references; uses of derivatives are distinguished from direct use of the acid.
Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.
Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.
Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.
Primary comparison identity. Explanations of structural differences are editorial interpretation of verified identities.
Related chemical identity; relevance is based on structure or the stated application relationship.
Related chemical identity; relevance is based on structure or the stated application relationship.
Related chemical identity; relevance is based on structure or the stated application relationship.
The primary comparison’s pKa source; reference conditions are preserved.
Succinate and fumarate in the citric acid cycle; salts/ions are distinguished from purchased free acids.
Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices.
This informational prototype is not a supplier, quotation service, or endorsement of a product’s fitness for an application. Buyers should verify the applicable specification, certification, and regulatory requirements for their intended use.