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CHEMICAL PROFILE CAS 90-64-2

Mandelic Acid

Properties, Uses, pKa, Safety,
Comparisons & Suppliers

Mandelic acid has a hydroxyl-bearing carbon between a benzene ring and a carboxyl group. That carbon is chiral, so a DL product is a different stereochemical choice from an R or S product. [1]

At a glance

Quick reference
Molecular formula
C₈H₈O₃ [1]
CAS number
90-64-2 [4]
Molecular weight
152.15 g/mol [1]
IUPAC name
2-hydroxy-2-phenylacetic acid [1]
Chemical family
Aromatic hydroxycarboxylic acid [1]
Carbon atoms
8 [1]
Carboxyl groups
1 [1]
pKa reference
Not verified in this review [2]

Identity focus: Solid · DL identity. Aqueous pKa values depend on conditions; product assay is a separate measurement.

01

THE ESSENTIALS

Mandelic Acid in 30 Seconds

The molecule combines a ring, a separate hydroxyl, and one acidic carboxyl group. The hydroxyl-bearing carbon is the point where its three-dimensional forms differ.

Mandelic acid has a hydroxyl-bearing carbon between a benzene ring and a carboxyl group. That carbon is chiral, so a DL product is a different stereochemical choice from an R or S product. [1] [3]

Mandelic Acid condensed structure: C₆H₅–CH(OH)–COOHC₆H₅–CH(OH)–COOHConnectivity schematic · stereochemistry specified separately

Condensed connectivity schematic; see the specified stereochemical identity below. [1]

01

Synthesis intermediates

Mandelic acid is used as a defined starting material for other chemical products. [3] [4]

02

Reaction research

The linked Sigma listing cites research on DL-mandelic-acid oxidation. [3] [4]

03

Formulation development

Mandelic acid is used in cosmetic formulation contexts. [3] [4]

04

Commercial availability

The supplier section separates package size, assay, grade, and market context for three named products. [4] [4]

02

GO A LITTLE DEEPER

Understanding Mandelic Acid

THE SIMPLE EXPLANATION

The functional groups

The molecule combines a ring, a separate hydroxyl, and one acidic carboxyl group. The hydroxyl-bearing carbon is the point where its three-dimensional forms differ. [1]

A LITTLE DEEPER

What the structure changes

Lactic acid has a methyl group where mandelic acid has a phenyl ring. Both have an alpha-hydroxyl, but the aromatic ring changes the structure and product identity. A high chemical assay does not establish enantiomeric purity. [1] [4] [5] [6]

Technical detail Identity, dissociation & specification

The selected products are DL-mandelic acid, CAS 90-64-2. R- and S-mandelic acid are separate stereochemical products. The connectivity drawing is not an enantiomer assignment. Numeric pKa is omitted because the reviewed record did not provide a verified value. [1] [2] [4] [5] [6]

Acid–base reference values describe equilibria under specified conditions. They are not a substitute for a validated formulation or an assay on the purchased lot.

03

MAKE THE CONNECTION

How Mandelic Acid Compares

Similar names and functional groups do not mean interchangeable chemicals.

SIDE-BY-SIDE COMPARISON

Mandelic Acid vs Lactic Acid

Aromatic hydroxycarboxylic acid
versus
Hydroxymonocarboxylic acid

Fixed comparison for this prototype. Acid selectors are disabled; additional comparisons are coming later.

Mandelic Acid compared with Lactic Acid
PropertyMandelic AcidLactic Acid
Molecular formulaC₈H₈O₃ [1]C₃H₆O₃ [7]
Molecular weight152.15 g/mol [1]90.08 g/mol [7]
Carbon atoms8 [1]3 [7]
Carboxyl groups1 [1]1 [7]
StructureC₆H₅–CH(OH)–COOH [1]CH₃–CH(OH)–COOH [7]
Chemical familyAromatic hydroxycarboxylic acid [1]Hydroxymonocarboxylic acid [7]
Identity focusSolid · DL identity [1]Commercial liquids / aqueous solutions [7]
Chemical identities are compared here; supplier grades, concentrations, and stereochemical specifications are separate purchasing attributes. pKa values retain their stated conditions; no quantitative solubility ranking is implied. The structure schematic does not encode stereochemistry.

When Might You Choose One Instead of the Other?

Use mandelic acid when the procedure needs its aromatic alpha-hydroxy framework and specified stereochemistry. Use lactic acid for the methyl-bearing framework. In chiral work, a DL supply is insufficient when the method requires a single enantiomer. [1] [3] [7]

Specified starting material

Mandelic Acid

Match C₆H₅–CH(OH)–COOH and the method’s required chemical form.

Lactic Acid

Match CH₃–CH(OH)–COOH; verify the identity before substituting a related acid.

Sources: [1] [7]

Before choosing: match the reaction or formulation, then verify the exact form, grade, assay basis, and impurities. These contexts do not establish suitability for an industrial or regulated application.

04

FROM STRUCTURE TO APPLICATION

What Is Mandelic Acid Used For?

01

Synthesis intermediates

Mandelic acid is used as a defined starting material for other chemical products. Specify DL or the required enantiomer before sourcing. [3] [4]

02

Reaction research

The linked Sigma listing cites research on DL-mandelic-acid oxidation. A research application does not establish suitability for other chemical forms. [3] [4]

03

Formulation development

Mandelic acid is used in cosmetic formulation contexts. These reagent listings do not establish cosmetic suitability or medical benefit. [3] [4]

05

CHOOSE THE RIGHT SPECIFICATION

Buying Mandelic Acid

Selecting mandelic acid involves more than the lowest price. Start with your application, then define purity, grade, quantity, documentation, and packaging.

1

What Are You Buying It For?

Intended use
Research / Synthesis

Specify DL, R, or S form and optical-purity requirements separately from chemical assay. Match the procedure’s identity and impurity specification; request a lot COA and current regional SDS.

2

Define Your Requirements

These are requirements you can request, not a list of guaranteed available combinations. Confirm each product’s actual specification.

Set your requirements to prepare a sourcing brief.
06

SOURCE WITH CONTEXT

Mandelic Acid Suppliers

Compare specific products and package options. Listings are not ranked recommendations.

3 suppliers · 3 products · 6 package listingsLatest supplier check: October 3, 2026

Package sizes stay grouped under the supplier product. Assay methods, product forms, and regional markets remain visible. Specify DL, R, or S form and optical-purity requirements separately from chemical assay.

Scroll horizontally if needed. Supplier and package identity stay visible.

6 package listings grouped under three supplier products
SupplierProduct / GradePurity / AssayPackage SizePublic PriceNormalized PriceDocumentationLast CheckedAction
Sigma-AldrichMandelic AcidFor synthesis · DL form8069130250≥99.0% (acidimetric)250 g$63.60USD · US public priceNot comparedGrades, assay bases, or forms differ
COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: Sigma-Aldrich
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.
View Product: Sigma-Aldrich, 8069130250 (opens new tab)
For synthesis · DL form8069131000≥99.0% (acidimetric)1 kg$195.00USD · US public priceNot comparedGrades, assay bases, or forms differView Product: Sigma-Aldrich, 8069131000 (opens new tab)
TCIMandelic AcidCheck supplierM0038DL form · CAS 90-64-2>99.0% (GC and titration)25 g$33.00USD · US public priceNot comparedGrades, assay bases, or forms differ
COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: TCI
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.
View Product: TCI, M0038 (opens new tab)
Check supplierM0038DL form · CAS 90-64-2>99.0% (GC and titration)500 g$89.00USD · US public priceNot comparedGrades, assay bases, or forms differView Product: TCI, M0038 (opens new tab)
FUJIFILM WakoMandelic AcidWako Special Grade · DL form013-03612≥99.0% (titration)25 g¥4,400JPY · Japan suggested price (tax excluded)Not comparedDifferent currency / market
Document notes: FUJIFILM Wako
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • The linked Japan/JIS English SDS covers the displayed product codes. Confirm the current local version.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.
View Product: FUJIFILM Wako, 013-03612 (opens new tab)
Wako Special Grade · DL form017-03615≥99.0% (titration)500 g¥21,800JPY · Japan suggested price (tax excluded)Not comparedDifferent currency / marketView Product: FUJIFILM Wako, 017-03615 (opens new tab)

Sigma-Aldrich

Mandelic Acid

≥99.0% (acidimetric)

For synthesis · DL form

250 g

8069130250
Public price
$63.60USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: Sigma-Aldrich, 8069130250 (opens new tab)

1 kg

8069131000
Public price
$195.00USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: Sigma-Aldrich, 8069131000 (opens new tab)

Documentation

COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: Sigma-Aldrich
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.

Last checked:

TCI

Mandelic Acid

>99.0% (GC and titration)

Check supplier
DL form · CAS 90-64-2

25 g

M0038
Public price
$33.00USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: TCI, M0038 (opens new tab)

500 g

M0038
Public price
$89.00USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: TCI, M0038 (opens new tab)

Documentation

COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: TCI
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.

Last checked:

FUJIFILM Wako

Mandelic Acid

≥99.0% (titration)

Wako Special Grade · DL form

25 g

013-03612
Public price
¥4,400JPY · Japan suggested price (tax excluded)
Normalized price
Not comparedDifferent currency / market
View Product: FUJIFILM Wako, 013-03612 (opens new tab)

500 g

017-03615
Public price
¥21,800JPY · Japan suggested price (tax excluded)
Normalized price
Not comparedDifferent currency / market
View Product: FUJIFILM Wako, 017-03615 (opens new tab)

Documentation

Document notes: FUJIFILM Wako
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • The linked Japan/JIS English SDS covers the displayed product codes. Confirm the current local version.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.

Last checked:

Documentation evidence

COA = Certificate of Analysis · SDS = Safety Data Sheet · COO = Certificate of Origin.

Lookup means a retrieval option was visible, not that a lot certificate was reviewed. Check supplier means availability or the applicable document was not verified.

Prices may vary by quantity, account, contract, geography, and availability. These products have different grades, assay bases, or forms; no normalized comparison is shown. Foreign-market prices are reference listings only. No currency conversion, mass-to-volume conversion, or ranking is applied. Confirm equivalent specifications and a current quote before comparison. [4] [5] [6]

Verification limits & placement policy

Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices.

Only the displayed identity, specification, packages, public prices and stated documentation evidence were reviewed. Current stock, lead times, shipping eligibility, contract pricing, lot certificates, and regulatory suitability are unverified.

There are no paid placements. Future paid listings will show “Sponsored” in both views; payment will not determine chemistry interpretation or imply a ranking.

07

PLAN A LARGER ORDER

Need Mandelic Acid in Bulk?

Turn your requirements into a clear supplier brief.

RFQ PROTOTYPE
Bulk RFQ feature — coming soon. Prototype form: submissions are not currently sent to suppliers. Use sample details to prepare an on-screen brief.
Prepare a bulk request Prototype form

The prefilled CAS identifies this profile’s principal form. Confirm or edit it for the requested product, especially a hydrate, stereoisomer, or salt. State the exact form and concentration before using the brief.

Prototype only · No request will be sent
08

A BUYER’S CHECKLIST

Before You Buy Mandelic Acid

Selections remain only while this page is open.

09

FOR YOUR REFERENCE

Mandelic Acid Technical Reference

Identity, product reference properties, and handling context.

Identification Names, formula & identifiers
Principal CAS
90-64-2
Identity focus
Solid · DL identity
Formula
C₈H₈O₃
Molecular weight
152.15 g/mol
IUPAC name
2-hydroxy-2-phenylacetic acid
Connectivity SMILES
C1=CC=C(C=C1)C(C(=O)O)O
PubChem CID
1292

Connectivity SMILES describes connectivity; it is not an independent stereochemical assignment. CAS and product-form distinctions are supported by the supplier listings. [1] [4] [5] [6]

Physical Properties Product references & conditions

Sigma lists crystals with melting range 119–121 °C and water solubility 139 g/L without a displayed temperature. This is a product reference, not a validated formulation limit. [4] [5] [6]

Hydrate, concentration, stereoisomer, and temperature can change the relevant specification. Product reference data are not a reviewed lot certificate.

Acid/Base Properties Verified values & missing data

A numeric pKa was not verified for the selected identity in this review; no value is inferred. [2]

Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices.

Temperature, ionic strength, and the use of activities versus concentrations matter in quantitative work. These reference values are not buffer recipes.

Safety Product-specific SDS
Review the current SDS for the exact product.

Match chemical form, concentration, region, and product code. Use its handling, storage, incompatibility, first-aid and disposal guidance alongside the workplace risk assessment.

A verified Japan/JIS English SDS is linked separately under supplier documentation; confirm the applicable local version. This profile is not a substitute for that document.

Review supplier documentation
10

COMMON QUESTIONS

Mandelic Acid FAQ

What distinguishes Mandelic Acid?

The molecule combines a ring, a separate hydroxyl, and one acidic carboxyl group. The hydroxyl-bearing carbon is the point where its three-dimensional forms differ. [1]

How does it differ from Lactic Acid?

Mandelic acid adds an aromatic phenyl group where lactic acid has a methyl group. The shared alpha-hydroxy-acid motif does not make either a substitute reagent or establish equivalent formulation behavior. [7]

What must a buyer specify?

Specify DL, R, or S form and optical-purity requirements separately from chemical assay. [4]

Are the listed products directly price-comparable?

No. The table retains differing grades, assay bases, forms, and markets. No normalized ranking or currency conversion is applied. [5]

What reference data still need checking?

Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices. [6]

Can I request a bulk quote here?

The RFQ is a prototype that prepares an on-screen brief. Nothing is sent to suppliers. Confirm actual bulk terms directly with the supplier. [4]

11

TRACE THE INFORMATION

Sources & Editorial Notes

Identity and compiled reference values are separated from supplier-specific specifications. Structural comparisons and buyer guidance are editorial interpretation. Sources were checked October 3, 2026; supplier information can change.

  1. PubChem · chemical identity (opens new tab)

    Official PUG REST identity record: formula, molecular weight, IUPAC name, and connectivity SMILES.

  2. PubChem · dissociation references (opens new tab)

    No usable numeric entry was retrieved for this selected identity; numeric pKa is deliberately omitted.

  3. PubChem · applications (opens new tab)

    Compiled application references; uses of derivatives are distinguished from direct use of the acid.

  4. Sigma-Aldrich · commercial product (opens new tab)

    Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.

  5. TCI · commercial product (opens new tab)

    Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.

  6. FUJIFILM Wako · commercial product (opens new tab)

    Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.

  7. Lactic Acid · identity (opens new tab)

    Primary comparison identity. Explanations of structural differences are editorial interpretation of verified identities.

  8. Benzoic Acid · identity (opens new tab)

    Related chemical identity; relevance is based on structure or the stated application relationship.

  9. Salicylic Acid · identity (opens new tab)

    Related chemical identity; relevance is based on structure or the stated application relationship.

  10. Malic Acid · identity (opens new tab)

    Related chemical identity; relevance is based on structure or the stated application relationship.

  11. Lactic Acid · acid–base reference (opens new tab)

    The primary comparison’s pKa source; reference conditions are preserved.

  12. OpenStax · Citric acid cycle (opens new tab)

    Succinate and fumarate in the citric acid cycle; salts/ions are distinguished from purchased free acids.

Review limits

Numeric pKa remains unverified. The supplier set describes DL material; single-enantiomer sourcing requires a separate review. Japan pricing is not normalized against US prices.

This informational prototype is not a supplier, quotation service, or endorsement of a product’s fitness for an application. Buyers should verify the applicable specification, certification, and regulatory requirements for their intended use.