Preservation applications
Propionic acid and propionate salts are used in preservation contexts. [3]
CHEMICAL PROFILE CAS 79-09-4
Properties, Uses, pKa, Safety,
Comparisons & Suppliers
Propionic acid is a three-carbon carboxylic acid. It connects short-chain organic chemistry with propionate preservation and industrial derivative production. [1]
Identity focus: Liquid. Aqueous pKa values depend on conditions; product assay is a separate measurement.
THE ESSENTIALS
The –COOH group is attached to a two-carbon chain. Adding one carbon relative to acetic acid gives a different molecule even though both have one acidic group.
Propionic acid is a three-carbon carboxylic acid. It connects short-chain organic chemistry with propionate preservation and industrial derivative production. [1] [3]
A condensed structural formula keeps the functional groups visible. [1]
Propionic acid and propionate salts are used in preservation contexts. [3]
A precursor for propionate esters and cellulose-propionate chemistry. [3]
Used as a defined three-carbon carboxylic starting material in specified synthetic procedures.. [3]
The supplier section separates package size, assay, grade, and market context for three named products. [4]
GO A LITTLE DEEPER
The –COOH group is attached to a two-carbon chain. Adding one carbon relative to acetic acid gives a different molecule even though both have one acidic group. [1]
Propionic acid and propionate salts share a chemical relationship but differ in counterion, formula, and handling. Lactic acid has the same carbon count but adds a hydroxyl group, so it is not the same reagent. [1] [4] [5] [6]
The compiled pKa is 4.88 without a stated condition in the selected entry. TCI’s assay uses both GC and titration; Wako’s value uses capillary GC. These measurements should not be assumed equivalent to an unspecified assay method. [1] [2] [4] [5] [6]
Acid–base reference values describe equilibria under specified conditions. They are not a substitute for a validated formulation or an assay on the purchased lot.
MAKE THE CONNECTION
Similar names and functional groups do not mean interchangeable chemicals.
SIDE-BY-SIDE COMPARISON
Fixed comparison for this prototype. Acid selectors are disabled; additional comparisons are coming later.
| Property | Propionic Acid | Acetic Acid |
|---|---|---|
| Molecular formula | C₃H₆O₂ [1] | C₂H₄O₂ [7] |
| Molecular weight | 74.08 g/mol [1] | 60.05 g/mol [7] |
| Carbon atoms | 3 [1] | 2 [7] |
| Carboxyl groups | 1 [1] | 1 [7] |
| Structure | CH₃–CH₂–COOH [1] | CH₃–COOH [7] |
| Chemical family | Aliphatic monocarboxylic acid [1] | Aliphatic monocarboxylic acid [7] |
| Identity focus | Liquid [1] | Concentrated liquid / glacial products [7] |
| pKa context | 4.88 (compiled; conditions unspecified) [2] | 4.76 (25 °C) [11] |
Choose propionic acid for a propionate or propionyl-related process that explicitly requires it. Acetic acid belongs in an acetate-based process. Preservation work needs an application-specific specification and validation rather than substitution by matching pKa. [1] [3] [7]
Match CH₃–CH₂–COOH and the method’s required chemical form.
Match CH₃–COOH; verify the identity before substituting a related acid.
Before choosing: match the reaction or formulation, then verify the exact form, grade, assay basis, and impurities. These contexts do not establish suitability for an industrial or regulated application.
FROM STRUCTURE TO APPLICATION
Propionic acid and propionate salts are used in preservation contexts. Specify the free acid or salt and the applicable use specification. [3]
A precursor for propionate esters and cellulose-propionate chemistry. Derivative properties do not describe the free acid. [3]
Used as a defined three-carbon carboxylic starting material in specified synthetic procedures. [3]
SOURCE WITH CONTEXT
Compare specific products and package options. Listings are not ranked recommendations.
Package sizes stay grouped under the supplier product. Assay methods, product forms, and regional markets remain visible. Distinguish propionic acid from sodium/calcium propionate and confirm the assay method.
Scroll horizontally if needed. Supplier and package identity stay visible.
| Supplier | Product / Grade | Purity / Assay | Package Size | Public Price | Normalized Price | Documentation | Last Checked | Action |
|---|---|---|---|---|---|---|---|---|
| Sigma-AldrichPropionic Acid | ACS reagent402907-100ML | ≥99.5% | 100 mL | $55.10USD · US public price | Not comparedGrades, assay bases, or forms differ | COA lookup on product page (opens new tab)SDSCheck supplierCOO lookup on product page (opens new tab) Document notes: Sigma-Aldrich
| View Product: Sigma-Aldrich, 402907-100ML (opens new tab) | |
| ACS reagent402907-500ML | ≥99.5% | 500 mL | $93.90USD · US public price | Not comparedGrades, assay bases, or forms differ | View Product: Sigma-Aldrich, 402907-500ML (opens new tab) | |||
| TCIPropionic Acid | Check supplierP0500 | >99.0% (GC and titration) | 25 mL | $22.00USD · US public price | Not comparedGrades, assay bases, or forms differ | Document notes: TCI
| View Product: TCI, P0500 (opens new tab) | |
| Check supplierP0500 | >99.0% (GC and titration) | 500 mL | $26.00USD · US public price | Not comparedGrades, assay bases, or forms differ | View Product: TCI, P0500 (opens new tab) | |||
| FUJIFILM WakoPropionic Acid | Wako Special Grade169-04723 | ≥98.0% (capillary GC) | 25 mL | $20.00USD · US list price | Not comparedGrades, assay bases, or forms differ | Document notes: FUJIFILM Wako
| View Product: FUJIFILM Wako, 169-04723 (opens new tab) | |
| Wako Special Grade163-04726 | ≥98.0% (capillary GC) | 500 mL | $24.00USD · US list price | Not comparedGrades, assay bases, or forms differ | View Product: FUJIFILM Wako, 163-04726 (opens new tab) |
Propionic Acid
ACS reagent
Last checked:
Propionic Acid
Check supplier
Last checked:
Propionic Acid
Wako Special Grade
Last checked:
COA = Certificate of Analysis · SDS = Safety Data Sheet · COO = Certificate of Origin.
Lookup means a retrieval option was visible, not that a lot certificate was reviewed. Check supplier means availability or the applicable document was not verified.
Prices may vary by quantity, account, contract, geography, and availability. These products have different grades, assay bases, or forms; no normalized comparison is shown. Foreign-market prices are reference listings only. No currency conversion, mass-to-volume conversion, or ranking is applied. Confirm equivalent specifications and a current quote before comparison. [4] [5] [6]
Wako’s linked US SDS returned 404 during review. Current regional documentation is still required. pKa conditions are not supplied in the selected compiled entry.
Only the displayed identity, specification, packages, public prices and stated documentation evidence were reviewed. Current stock, lead times, shipping eligibility, contract pricing, lot certificates, and regulatory suitability are unverified.
There are no paid placements. Future paid listings will show “Sponsored” in both views; payment will not determine chemistry interpretation or imply a ranking.
PLAN A LARGER ORDER
Turn your requirements into a clear supplier brief.
A BUYER’S CHECKLIST
Selections remain only while this page is open.
FOR YOUR REFERENCE
Identity, product reference properties, and handling context.
Connectivity SMILES describes connectivity; it is not an independent stereochemical assignment. CAS and product-form distinctions are supported by the supplier listings. [1] [4] [5] [6]
Reference pKa: 4.88 (compiled; conditions unspecified). [2]
Wako’s linked US SDS returned 404 during review. Current regional documentation is still required. pKa conditions are not supplied in the selected compiled entry.
Temperature, ionic strength, and the use of activities versus concentrations matter in quantitative work. These reference values are not buffer recipes.
Match chemical form, concentration, region, and product code. Use its handling, storage, incompatibility, first-aid and disposal guidance alongside the workplace risk assessment.
A current regional SDS remains to be verified; the supplier documentation field says Check supplier. This profile is not a substitute for that document.
Review supplier documentationCOMMON QUESTIONS
The –COOH group is attached to a two-carbon chain. Adding one carbon relative to acetic acid gives a different molecule even though both have one acidic group. [1]
Propionic acid has a longer carbon chain than acetic acid. That changes the organic fragment delivered to a synthesis and the identity of the resulting salt or ester. [7]
Distinguish propionic acid from sodium/calcium propionate and confirm the assay method. [4]
No. The table retains differing grades, assay bases, forms, and markets. No normalized ranking or currency conversion is applied. [5]
Wako’s linked US SDS returned 404 during review. Current regional documentation is still required. pKa conditions are not supplied in the selected compiled entry. [6]
The RFQ is a prototype that prepares an on-screen brief. Nothing is sent to suppliers. Confirm actual bulk terms directly with the supplier. [4]
TRACE THE INFORMATION
Identity and compiled reference values are separated from supplier-specific specifications. Structural comparisons and buyer guidance are editorial interpretation. Sources were checked October 3, 2026; supplier information can change.
Official PUG REST identity record: formula, molecular weight, IUPAC name, and connectivity SMILES.
Compiled reference entries; their methods and conditions matter. Citric acid’s displayed stepwise values are from the linked Sigma specification.
Compiled application references; uses of derivatives are distinguished from direct use of the acid.
Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.
Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.
Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.
Primary comparison identity. Explanations of structural differences are editorial interpretation of verified identities.
Related chemical identity; relevance is based on structure or the stated application relationship.
Related chemical identity; relevance is based on structure or the stated application relationship.
Related chemical identity; relevance is based on structure or the stated application relationship.
The primary comparison’s pKa source; reference conditions are preserved.
Succinate and fumarate in the citric acid cycle; salts/ions are distinguished from purchased free acids.
Wako’s linked US SDS returned 404 during review. Current regional documentation is still required. pKa conditions are not supplied in the selected compiled entry.
This informational prototype is not a supplier, quotation service, or endorsement of a product’s fitness for an application. Buyers should verify the applicable specification, certification, and regulatory requirements for their intended use.