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CHEMICAL PROFILE CAS 107-92-6

Butyric Acid

Properties, Uses, pKa, Safety,
Comparisons & Suppliers

Butyric acid is the straight-chain four-carbon monocarboxylic acid. It is a starting material for butyrate derivatives and a distinct product from branched isobutyric acid or butyrate salts. [1]

At a glance

Quick reference
Molecular formula
C₄H₈O₂ [1]
CAS number
107-92-6 [4]
Molecular weight
88.11 g/mol [1]
IUPAC name
butanoic acid [1]
Chemical family
Aliphatic monocarboxylic acid [1]
Carbon atoms
4 [1]
Carboxyl groups
1 [1]
pKa reference
4.82 (25 °C) [2]

Identity focus: Liquid. Aqueous pKa values depend on conditions; product assay is a separate measurement.

01

THE ESSENTIALS

Butyric Acid in 30 Seconds

Three carbons form a chain attached to one –COOH group. Despite having four carbon atoms, it does not have the two acidic ends of succinic acid.

Butyric acid is the straight-chain four-carbon monocarboxylic acid. It is a starting material for butyrate derivatives and a distinct product from branched isobutyric acid or butyrate salts. [1] [3]

Butyric Acid condensed structure: CH₃–CH₂–CH₂–COOHCH₃–CH₂–CH₂–COOH1 carboxyl group

A condensed structural formula keeps the functional groups visible. [1]

01

Ester intermediates

Butyric acid is used to make butyrate esters for specified fragrance and flavor applications. [3]

02

Industrial derivatives

Used in chemistry involving cellulose derivatives and other specified intermediates.. [3]

03

Research chemistry

Butyrate-related research needs explicit chemical form and experimental conditions. [3]

04

Commercial availability

The supplier section separates package size, assay, grade, and market context for three named products. [4]

02

GO A LITTLE DEEPER

Understanding Butyric Acid

THE SIMPLE EXPLANATION

The functional groups

Three carbons form a chain attached to one –COOH group. Despite having four carbon atoms, it does not have the two acidic ends of succinic acid. [1]

A LITTLE DEEPER

What the structure changes

A butyrate salt and a butyrate ester differ from free butyric acid. Discussions of biological butyrate or ester flavor applications should not be read as claims about using concentrated free acid. [1] [4] [5] [6]

Technical detail Identity, dissociation & specification

The Sigma specification labels GC purity as area percent. That is a measurement basis, not an automatically interchangeable mass-fraction assay. The page uses the straight-chain identity CAS 107-92-6. [1] [2] [4] [5] [6]

Acid–base reference values describe equilibria under specified conditions. They are not a substitute for a validated formulation or an assay on the purchased lot.

03

MAKE THE CONNECTION

How Butyric Acid Compares

Similar names and functional groups do not mean interchangeable chemicals.

SIDE-BY-SIDE COMPARISON

Butyric Acid vs Propionic Acid

Aliphatic monocarboxylic acid
versus
Aliphatic monocarboxylic acid

Fixed comparison for this prototype. Acid selectors are disabled; additional comparisons are coming later.

Butyric Acid compared with Propionic Acid
PropertyButyric AcidPropionic Acid
Molecular formulaC₄H₈O₂ [1]C₃H₆O₂ [7]
Molecular weight88.11 g/mol [1]74.08 g/mol [7]
Carbon atoms4 [1]3 [7]
Carboxyl groups1 [1]1 [7]
StructureCH₃–CH₂–CH₂–COOH [1]CH₃–CH₂–COOH [7]
Chemical familyAliphatic monocarboxylic acid [1]Aliphatic monocarboxylic acid [7]
Identity focusLiquid [1]Liquid [7]
pKa context4.82 (25 °C) [2]4.88 (compiled; conditions unspecified) [11]
Chemical identities are compared here; supplier grades, concentrations, and stereochemical specifications are separate purchasing attributes. pKa values retain their stated conditions; no quantitative solubility ranking is implied.

When Might You Choose One Instead of the Other?

Choose butyric acid for the specified straight-chain butyrate route. Choose propionic acid for a propionate route. In research, establish whether the protocol needs free acid or a particular salt and counterion. [1] [3] [7]

Specified starting material

Butyric Acid

Match CH₃–CH₂–CH₂–COOH and the method’s required chemical form.

Propionic Acid

Match CH₃–CH₂–COOH; verify the identity before substituting a related acid.

Sources: [1] [7]

Before choosing: match the reaction or formulation, then verify the exact form, grade, assay basis, and impurities. These contexts do not establish suitability for an industrial or regulated application.

04

FROM STRUCTURE TO APPLICATION

What Is Butyric Acid Used For?

01

Ester intermediates

Butyric acid is used to make butyrate esters for specified fragrance and flavor applications. These applications concern the derivative, not direct use of the free acid. [3]

02

Industrial derivatives

Used in chemistry involving cellulose derivatives and other specified intermediates. [3]

03

Research chemistry

Butyrate-related research needs explicit chemical form and experimental conditions. A salt-based protocol cannot be silently replaced with the free acid. [3]

05

CHOOSE THE RIGHT SPECIFICATION

Buying Butyric Acid

Selecting butyric acid involves more than the lowest price. Start with your application, then define purity, grade, quantity, documentation, and packaging.

1

What Are You Buying It For?

Intended use
Research / Synthesis

Specify straight-chain acid versus isobutyric acid or butyrate salt; retain GC area-percent basis. Match the procedure’s identity and impurity specification; request a lot COA and current regional SDS.

2

Define Your Requirements

These are requirements you can request, not a list of guaranteed available combinations. Confirm each product’s actual specification.

Set your requirements to prepare a sourcing brief.
06

SOURCE WITH CONTEXT

Butyric Acid Suppliers

Compare specific products and package options. Listings are not ranked recommendations.

3 suppliers · 3 products · 6 package listingsLatest supplier check: October 3, 2026

Package sizes stay grouped under the supplier product. Assay methods, product forms, and regional markets remain visible. Specify straight-chain acid versus isobutyric acid or butyrate salt; retain GC area-percent basis.

Scroll horizontally if needed. Supplier and package identity stay visible.

6 package listings grouped under three supplier products
SupplierProduct / GradePurity / AssayPackage SizePublic PriceNormalized PriceDocumentationLast CheckedAction
Sigma-AldrichButyric AcidFor synthesis8004570100≥99% (GC; area %)100 mL$37.60USD · US public priceNot comparedGrades, assay bases, or forms differ
COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: Sigma-Aldrich
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.
View Product: Sigma-Aldrich, 8004570100 (opens new tab)
For synthesis8004571000≥99% (GC; area %)1 L$64.50USD · US public priceNot comparedGrades, assay bases, or forms differView Product: Sigma-Aldrich, 8004571000 (opens new tab)
TCIButyric AcidCheck supplierB0754>99.0% (GC and titration)25 mL$17.00USD · US public priceNot comparedGrades, assay bases, or forms differ
COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: TCI
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.
View Product: TCI, B0754 (opens new tab)
Check supplierB0754>99.0% (GC and titration)500 mL$29.00USD · US public priceNot comparedGrades, assay bases, or forms differView Product: TCI, B0754 (opens new tab)
FUJIFILM WakoButyric AcidWako Special Grade029-05393≥98.0% (capillary GC)25 mL$45.00USD · US list priceNot comparedGrades, assay bases, or forms differ
COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: FUJIFILM Wako
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.
View Product: FUJIFILM Wako, 029-05393 (opens new tab)
Wako Special Grade023-05396≥98.0% (capillary GC)500 mL$61.00USD · US list priceNot comparedGrades, assay bases, or forms differView Product: FUJIFILM Wako, 023-05396 (opens new tab)

Sigma-Aldrich

Butyric Acid

≥99% (GC; area %)

For synthesis

100 mL

8004570100
Public price
$37.60USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: Sigma-Aldrich, 8004570100 (opens new tab)

1 L

8004571000
Public price
$64.50USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: Sigma-Aldrich, 8004571000 (opens new tab)

Documentation

COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: Sigma-Aldrich
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.

Last checked:

TCI

Butyric Acid

>99.0% (GC and titration)

Check supplier

25 mL

B0754
Public price
$17.00USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: TCI, B0754 (opens new tab)

500 mL

B0754
Public price
$29.00USD · US public price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: TCI, B0754 (opens new tab)

Documentation

COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: TCI
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.

Last checked:

FUJIFILM Wako

Butyric Acid

≥98.0% (capillary GC)

Wako Special Grade

25 mL

029-05393
Public price
$45.00USD · US list price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: FUJIFILM Wako, 029-05393 (opens new tab)

500 mL

023-05396
Public price
$61.00USD · US list price
Normalized price
Not comparedGrades, assay bases, or forms differ
View Product: FUJIFILM Wako, 023-05396 (opens new tab)

Documentation

COA lookup on product page (opens new tab)SDSCheck supplierCOOCheck supplier
Document notes: FUJIFILM Wako
  • A product-specific certificate retrieval option was visible; no lot certificate was reviewed. Open the product page and use its certificate section.
  • A current regional SDS was not verified in this pass.
  • Origin-document availability was not verified. Country of origin is unverified and is not inferred.

Last checked:

Documentation evidence

COA = Certificate of Analysis · SDS = Safety Data Sheet · COO = Certificate of Origin.

Lookup means a retrieval option was visible, not that a lot certificate was reviewed. Check supplier means availability or the applicable document was not verified.

Prices may vary by quantity, account, contract, geography, and availability. These products have different grades, assay bases, or forms; no normalized comparison is shown. Foreign-market prices are reference listings only. No currency conversion, mass-to-volume conversion, or ranking is applied. Confirm equivalent specifications and a current quote before comparison. [4] [5] [6]

Verification limits & placement policy

Conflicting TCI water-solubility descriptions need manual review. Supplier assays use different methods and bases.

Only the displayed identity, specification, packages, public prices and stated documentation evidence were reviewed. Current stock, lead times, shipping eligibility, contract pricing, lot certificates, and regulatory suitability are unverified.

There are no paid placements. Future paid listings will show “Sponsored” in both views; payment will not determine chemistry interpretation or imply a ranking.

07

PLAN A LARGER ORDER

Need Butyric Acid in Bulk?

Turn your requirements into a clear supplier brief.

RFQ PROTOTYPE
Bulk RFQ feature — coming soon. Prototype form: submissions are not currently sent to suppliers. Use sample details to prepare an on-screen brief.
Prepare a bulk request Prototype form

The prefilled CAS identifies this profile’s principal form. Confirm or edit it for the requested product, especially a hydrate, stereoisomer, or salt. State the exact form and concentration before using the brief.

Prototype only · No request will be sent
08

A BUYER’S CHECKLIST

Before You Buy Butyric Acid

Selections remain only while this page is open.

09

FOR YOUR REFERENCE

Butyric Acid Technical Reference

Identity, product reference properties, and handling context.

Identification Names, formula & identifiers
Principal CAS
107-92-6
Identity focus
Liquid
Formula
C₄H₈O₂
Molecular weight
88.11 g/mol
IUPAC name
butanoic acid
Connectivity SMILES
CCCC(=O)O
PubChem CID
264

Connectivity SMILES describes connectivity; it is not an independent stereochemical assignment. CAS and product-form distinctions are supported by the supplier listings. [1] [4] [5] [6]

Physical Properties Product references & conditions

Sigma reports melting range −8 to −5 °C and boiling range 162–165 °C at 1013 mbar. TCI simultaneously describes complete water miscibility and 56.4 g/L at 25 °C; these statements conflict and no solubility ranking is made. [4] [5] [6]

Hydrate, concentration, stereoisomer, and temperature can change the relevant specification. Product reference data are not a reviewed lot certificate.

Acid/Base Properties Verified values & missing data

Reference pKa: 4.82 (25 °C). [2]

Conflicting TCI water-solubility descriptions need manual review. Supplier assays use different methods and bases.

Temperature, ionic strength, and the use of activities versus concentrations matter in quantitative work. These reference values are not buffer recipes.

Safety Product-specific SDS
Review the current SDS for the exact product.

Match chemical form, concentration, region, and product code. Use its handling, storage, incompatibility, first-aid and disposal guidance alongside the workplace risk assessment.

A current regional SDS remains to be verified; the supplier documentation field says Check supplier. This profile is not a substitute for that document.

Review supplier documentation
10

COMMON QUESTIONS

Butyric Acid FAQ

What distinguishes Butyric Acid?

Three carbons form a chain attached to one –COOH group. Despite having four carbon atoms, it does not have the two acidic ends of succinic acid. [1]

How does it differ from Propionic Acid?

Propionic acid is shorter by one carbon. The chain length changes the resulting carboxylate or ester identity, even though both are liquid monocarboxylic acids. [7]

What must a buyer specify?

Specify straight-chain acid versus isobutyric acid or butyrate salt; retain GC area-percent basis. [4]

Are the listed products directly price-comparable?

No. The table retains differing grades, assay bases, forms, and markets. No normalized ranking or currency conversion is applied. [5]

What reference data still need checking?

Conflicting TCI water-solubility descriptions need manual review. Supplier assays use different methods and bases. [6]

Can I request a bulk quote here?

The RFQ is a prototype that prepares an on-screen brief. Nothing is sent to suppliers. Confirm actual bulk terms directly with the supplier. [4]

11

TRACE THE INFORMATION

Sources & Editorial Notes

Identity and compiled reference values are separated from supplier-specific specifications. Structural comparisons and buyer guidance are editorial interpretation. Sources were checked October 3, 2026; supplier information can change.

  1. PubChem · chemical identity (opens new tab)

    Official PUG REST identity record: formula, molecular weight, IUPAC name, and connectivity SMILES.

  2. PubChem · dissociation references (opens new tab)

    Compiled reference entries; their methods and conditions matter. Citric acid’s displayed stepwise values are from the linked Sigma specification.

  3. PubChem · applications (opens new tab)

    Compiled application references; uses of derivatives are distinguished from direct use of the acid.

  4. Sigma-Aldrich · commercial product (opens new tab)

    Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.

  5. TCI · commercial product (opens new tab)

    Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.

  6. FUJIFILM Wako · commercial product (opens new tab)

    Direct product listing checked October 3, 2026. Product-specific grade, assay, package, public price and documentation retrieval evidence.

  7. Propionic Acid · identity (opens new tab)

    Primary comparison identity. Explanations of structural differences are editorial interpretation of verified identities.

  8. Acetic Acid · identity (opens new tab)

    Related chemical identity; relevance is based on structure or the stated application relationship.

  9. Succinic Acid · identity (opens new tab)

    Related chemical identity; relevance is based on structure or the stated application relationship.

  10. Lactic Acid · identity (opens new tab)

    Related chemical identity; relevance is based on structure or the stated application relationship.

  11. Propionic Acid · acid–base reference (opens new tab)

    The primary comparison’s pKa source; reference conditions are preserved.

  12. OpenStax · Citric acid cycle (opens new tab)

    Succinate and fumarate in the citric acid cycle; salts/ions are distinguished from purchased free acids.

Review limits

Conflicting TCI water-solubility descriptions need manual review. Supplier assays use different methods and bases.

This informational prototype is not a supplier, quotation service, or endorsement of a product’s fitness for an application. Buyers should verify the applicable specification, certification, and regulatory requirements for their intended use.